The results suggest that mastic significantly decreased the activity index and the plasma levels of IL-6 and CRP in patients with mildly to moderately active CD (Kaliora 2007).

Researchers (Huwez et al 1998) in the New England Journal of Medicine reported that mastic is an effective antibacterial agent for the treatment of H. pylori. Authors stated that, “Even low doses of mastic gum – one gram per day for two weeks – can cure peptic ulcers very rapidly… We have found that mastic is active against Helicobacter pylori, which could explain its therapeutic effect in patients with peptic ulcers.”

Dabos et al.  (2010) showed Chios mastic gum significantly improved symptoms in patients with functional dyspepsia compared to a placebo.

One comprehensive review looked at the antimicrobial, antifungal, antioxidant, hypolipidemic, anti-inflammatory, anti-Crohn & anticancer activities associated with mastic gum.